| If you are in between sizes and weigh 80 kg+ (175+ lbs) with a chest size of 112cm (44") or more, then choose the H250.
A tall person up to about 190cm (6'3") can wear the smaller H245 harness, however it just won't fit as well as a H250 would--the padded straps won't wrap down in front as far and the sternum strap may catch you in the neck. A smaller person, on the other hand, cannot wear the H250 harness as the straps in front won't cinch down.
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